Plenary Lecture

 

Lucia Banci

Perspectives in inorganic structural biology

 

NO Synthase

Michael A. Marletta, Amy R. Hurshman, and Kristin M. Rusche

Nitric Oxide synthase: piecing together catalysis

 

C. S. Raman, H. Li, P. Martasek, V. Kral, B. S. S. Masters, and Thomas L. Poulos

Crystal structure of nitric oxide synthase heme domains

 

David L. Tierney, Peter E. Doan, Hui Huang, Pavel Martasek, Bettie Sue Siler Masters, Richard B. Silverman, and Brian M. Hoffman

ENDOR spectroscopic determination of the position and structure of enzyme-bound substrates: holo- nitric oxide synthase

Biodegradation

Georg Fuchs

New metalloenzymes in the anaerobic aromatic metabolism of bacteria

 

Lindsay D. Eltis

The suicide inhibition of 2,3-dihydroxybiphenyl dioxygenase by PCB metabolites

 

Enrique Carredano, Björn Kauppi, Devapriya Choudhury, Rebecca E. Parales, Kyoung Lee, David T. Gibson, Hans Eklund, and S. Ramaswamy

Implications for substrate specificity of naphthalene 1,2-dioxygenase from the refined crystal structure

Hydrogenase

Baerbel Friedrich, Christian Massanz, Michael Bernhard, and Oliver Lenz

[NiFe] hydrogenases: variations of a common theme

 

John W. Peters, William N. Lanzilotta, Brian J. Lemon, Lance C. Seefeldt

X-ray structure of the Fe-only hydrogenase (CpI) from Clostridium pasteurianum

 

Stephen A. Koch, Hua-Fen Hsu, Sechin Chang, Andrew Acunzo, and Jianfeng Jiang

The unprecedented [Fe(CN)₂(CO)] and [Fe(CN)(CO)] centers in hydrogenase enzymes? Why did nature choose such combinations of vile ligands?

 

Hideaki Ogata, Kunio Miki, Noritake Yasuoka, Tatsuhiko Yagi, and Yoshiki Higuchi

New crystallographic and chemical insights into the activation of NiFe-hydrogenase by H₂

 

Protein Radicals

Stuart Licht, Christopher Lawrence, Brenda Kellogg, and JoAnne Stubbe

Class II ribonucleotide reductases: adenosylcobalamin as a radical chain initiator of a reaction with a chain length of one

 

Astrid Gräslund

Formation and reactions of the iron/tyrosyl radical site in ribonucleotide reductase

 

Marc Fontecave

The anaerobic ribonucleotide reductase: a radical/iron-sulfur enzyme

 

Joan B. Broderick, Timothy F. Henshaw, and Sheila S. Smith

Pyruvate formate-lyase activase: iron-sulfur clusters in radical generation

Metals in Medicine

 

Nicholas Farrell

Structurally novel platinum-based drugs in the clinic. Toward a new paradigm

 

Trevor W. Hambley, Susan J. Berners-Price, Murray S. Davies, Connie I. Diakos, Hui Meng Er, Ronald R. Fenton, Edwina C. H. Ling, Vivienne P. Munk, and Evonne M. Rezler

What controls Pt/DNA interactions?

 

Randall B. Lauffer

Biophysical tuning and targeting of gadolinium(III) chelates for MRI

 

Thomas J. Meade

Seeing is believing: monitoring in vivo gene expression by magnetic resonance imaging

O₂ Toxicity

Anne-Frances Miller, Aaron L. Schwartz, and Carrie K. Vance

Mechanisms of redox tuning in Fe- and Mn-superoxide dismutases

 

Michael J. Maroney, Suranjan B. Choudhury, Jin-Won Lee, Gerard Davidson, Yang-In Yim, Kurethara Bose, Manju L. Sharma, Sa-Ouk Kang, and Diane E. Cabelli

A SOD story: The structure and function of the NiSOD active site

 

Miguel Teixeira, Célia Romão, Cláudio Gomes, Jean LeGall, and A. V. Xavier

New metalloproteins involved in oxygen stress response in anaerobes

 

Joan Selverstone Valentine, Edith Butler Gralla, Joy J. Goto, Hongbin Liu, and Haining Zhu

Copper-zinc superoxide dismutase and ALS

 

 

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