Plenary Lecture

Edward I. Solomon

Geometric and electronic structure contributions to function in non-heme iron enzymes

 

Computational Chemistry

Margareta R. A. Blomberg

Mechanisms for O-O bond activation in cytochrome c oxidase and haem-peroxidases

 

Kazunari Yoshizawa

Two-step concerted mechanism for methane hydroxylation on the diiron centers of methane monooxygenase

 

Abhik Ghosh

Theoretical modeling of metalloporphyrins and heme proteins

O₂ Intermediates

Ilme Schlichting, Joel Berendzen, Kelvin Chu, Ann M. Stock, Robert M. Sweet, Dagmar Ringe, Gregory A. Petsko, Matthew Davies, Nancy C. Gerber, Ernest J. Mueller, David Benson, Momcilo Vidakovic, and Stephen G. Sligar

Crystal structures of intermediates occurring along the reaction coordinate of cytochrome P450_cam

 

Carsten Krebs, Dale E. Edmondson, and Boi Hanh Huynh

Rapid freeze-quench Mössbauer investigations of intermediates in oxygen activation reactions of carboxylate-bridged diiron proteins

 

Brian G. Fox

Catalytic and spectroscopic studies of stearoyl-ACP D ⁹ desaturase (D 9D)

 

Carrie M. Wilmot, Janos Hajdu, Colin G. Saysell, Michael J. McPherson, Peter F. Knowles, and Simon E. V. Phillips

A movie of catalysis in the copper-containing quinoenzyme amine oxidase

Cluster Models

R. H. Holm, Christine A. Goddard, Richard Koerner, Catalina E. Laplaza, Booyong S. Lim, Alexander Nivorozhkin, and Frank Osterloh

Synthetic representations of mononuclear and bridged polynuclear enzyme active sites

 

Charles G. Riordan, Beaven Mandimutsira, and Janis Voo

Synthetic and mechanistic studies related to acetyl coenzyme A synthase

 

Annie K. Powell

Approaches to modelling iron storage in ferritins

 

Cofactor Assembly

M. K. Johnson, P. Yuvaniyama, J. N. Agar, V. L. Cash, and D. R. Dean

Biological formation of iron-sulfur clusters

 

Ralf R. Mendel

Molybdenum cofactor biosynthesis in plants and humans

 

J. M. Bollinger, Jr., J. Baldwin, C. Krebs, P. Moënne-Loccoz, W. C. Voegtli, N. Khidekel, S. Chen, B. A. Ley, D. E. Edmondson, B. H. Huynh, T. M. Loehr, and A. C. Rosenzweig

Structural determinants of the mechanisms and outcomes of O₂ activation by the diiron carboxylate proteins

 

David M. Dooley, John Bollinger, Michele McGuirl, Christy Ruggiero, and Melanie Rogers

Biogenesis and biosynthesis of catalytic sites in copper-containing amine oxidases, galactose oxidase, and nitrous oxide reductase

 

Long Range Transfer

Harry B. Gray and Jay R. Winkler

Electron tunneling in metalloproteins

 

Britt-Marie Sjöberg, Monica Ekberg, Annika Persson, and Margareta Sahlin

Transient radicals and coupled electron/proton transfer in ribonucleotide reductase

 

Mårten Wikström, Audrius Jasaitis, Joel E. Morgan, and Michael I. Verkhovsky

Proton translocation by cytochrome c oxidase

 

Fraser A. Armstrong

Electron-transfer coupling and gating in proteins: unravelling reaction steps and detecting intermediates by protein-film voltammetry

 

Metalloprotein Design

John P. Caradonna, Ann L. Pinto, Christopher D. Coldren, and Yu Wang

Incorporation of metal-based active sites into host proteins by rational protein design methods

 

Yoshihito Watanabe

Rational molecular design of a catalytic site: Engineering of catalytic functions to the myoglobin active site framework

 

Gerard W. Canters, Christian Buning, Peter Comba, Christopher Dennison, Lars Jeuken, Michael Melter, Joann Sanders-Loehr, Pieter van Vliet, and Irene van Amsterdam

Engineering of copper containing active sites and construction of ET maquettes

 

Yi Lu

Redesigning metalloproteins

 

Plenary Lecture

Phalguni Chaudhuri, Martina Hess, and Karl Wieghardt

From structural models to homogeneous catalysis: the biomimetic approach

 

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