Plenary Lecture

 

Judith Klinman

Life as aerobes: are there simple principles for enzyme catalysis of dioxygen activation?

 

 

O₂ Activation Models

 

Yadong Wang, Robertus J. M. Klein Gebbink, Jennifer Dubois, Britt Hedman, Keith Hodgson, and T. Daniel P. Stack

Capturing the essence of a metalloenzyme

 

Shinobu Itoh, Masayasu Taki, Patrick Holland, William B. Tolman, Lawrence Que, Jr., and Shunichi Fukuzumi

Dioxygen activation mechanism by synthetic copper complexes

 

Marius Réglier

Substrate binding ligand approach in chemical modeling of Cu-containing monooxygenases

New Metalloenzymes

Roopali Roy, Gerrit J. Schut, Yonglin Hu, Douglas C. Rees, and Michael W. W. Adams

Tungstoenzymes from microorganisms that grow at 100° C

 

John Shanklin and Ed. Whittle

Integral membrane diiron proteins: A distinct and widespread group of enzymes with diverse catalytic plasticity

 

Simon de Vries, Ton C. Mulder, Marc J. F. Strampraad, Oliver M. H. Richter, and Pierre Moënne-Loccoz

Structural and functional characterization of the active site of NO reductase and comparison to bc-type oxidases

 

Heme Chemistry

Bernard Meunier

The role of heme in the action of antimalarial drugs related to artemisinin

 

John T. Groves, Jinbo Lee, Julianne A. Hunt, Roman Shimanovich, and Ning Jin

Mechanisms of metalloporphyrin reactions with peroxynitrite

 

Zeev Gross, Nitsa Galili, and Liliya Simkhovich

Corroles, ligands of the future

 

C1 Chemistry

Rudolf K. Thauer

Structure and function of the nickel enzyme methyl-coenzyme M reductase

 

Mona Damaj, Jian Feng, Huay-Keng Loke, Ernest L. Maynard, and Paul A. Lindahl

Structure, function, and biosynthesis of the novel Ni-X-Fe₄S₄ clusters of acetyl-coenzyme A synthase (carbon monoxide dehydrogenase)

 

Jessica L. Blazyk, Hans Brandstetter, Christin A. Frederick, George T. Gassner, Daniel A. Kopp, Stephen J. Lippard, Shannon S. Stahl, Ann M. Valentine, Gerhard Wagner, Kylie J. Walters, and Douglas A. Whittington

The soluble methane monooxygenase: components and catalysis

 

Sunney I. Chan

Dioxygen activation and alkane hydroxylation by the membrane-bound methane monooxygenase in methanotrophic bacteria

 

Nitrile Hydratase/Urease

Isao Endo, Masayoshi Nakasako, Shigehiro Nagashima, Naoshi Dohmae, Masanari Tsujimura, Koji Takio, Masafumi Odaka, Masafumi Yohda, and Nobuo Kamiya

Structure and function of a photoreactive enzyme, nitrile hydratase: crystal structure analysis of the inactive enzyme at 1.7Å resolution

 

Isabelle Artaud

Nitrile hydratase: a non-heme enzyme with sulfinic and sulfenic groups in the iron environment to catalyze nitrile hydration

 

Stefano Ciurli, Stefano Benini, Wojciech R. Rypniewski, Keith S. Wilson, Silvia Miletti, and Stefano Mangani

Structure-based mechanism for urease: why urea hydrolysis costs two nickels

 

Robert P. Hausinger

Assembly of the urease dinuclear Ni active site

 

Sensing

Judith N. Burstyn

Regulation of NO-sensing soluble guanylyl cyclase and CO-sensing CooA

 

Shigetoshi Aono and Hiroshi Nakajima

Regulation of gene expression with the CO-sensing transcriptional activator CooA

 

Eckard Münck, Codrina Popescu, Donna Bates, Helmut Beinert, and Patricia J. Kiley

Mössbauer studies of the transcription factor FNR in whole cells of E. coli

 

Isabelle Michaud-Soret, Annie Adrait, François Dole, Anne Gonzalez de Peredo, Lilian Jacquamet, Claudine Jeandey, Laurent Le Pape, Jean-Louis Oddou, Emmanuel Perret, and Jean-Marc Latour

Fur, the iron sensor protein in bacteria: spectroscopic, magnetic and structural characterization

 

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