Plenary Lecture
Lucia BanciPerspectives in inorganic structural biology
NO Synthase
Michael A. Marletta, Amy R. Hurshman, and Kristin M. RuscheNitric Oxide synthase: piecing together catalysis
C. S. Raman, H. Li, P. Martasek, V. Kral, B. S. S. Masters, and Thomas L. Poulos
Crystal structure of nitric oxide synthase heme domains
David L. Tierney, Peter E. Doan, Hui Huang, Pavel Martasek, Bettie Sue Siler Masters, Richard B. Silverman, and Brian M. Hoffman
ENDOR spectroscopic determination of the position and structure of enzyme-bound substrates: holo- nitric oxide synthase
Biodegradation
Georg FuchsNew metalloenzymes in the anaerobic aromatic metabolism of bacteria
Lindsay D. Eltis
The suicide inhibition of 2,3-dihydroxybiphenyl dioxygenase by PCB metabolites
Enrique Carredano, Björn Kauppi, Devapriya Choudhury, Rebecca E. Parales, Kyoung Lee, David T. Gibson, Hans Eklund, and S. Ramaswamy
Implications for substrate specificity of naphthalene 1,2-dioxygenase from the refined crystal structure
Hydrogenase
Baerbel Friedrich, Christian Massanz, Michael Bernhard, and Oliver Lenz[NiFe] hydrogenases: variations of a common theme
John W. Peters, William N. Lanzilotta, Brian J. Lemon, Lance C. Seefeldt
X-ray structure of the Fe-only hydrogenase (CpI) from Clostridium pasteurianum
Stephen A. Koch, Hua-Fen Hsu, Sechin Chang, Andrew Acunzo, and Jianfeng Jiang
The unprecedented [Fe(CN)2(CO)] and [Fe(CN)(CO)] centers in hydrogenase enzymes? Why did nature choose such combinations of vile ligands?
Hideaki Ogata, Kunio Miki, Noritake Yasuoka, Tatsuhiko Yagi, and Yoshiki Higuchi
New crystallographic and chemical insights into the activation of NiFe-hydrogenase by H2
Protein Radicals
Stuart Licht, Christopher Lawrence, Brenda Kellogg, and JoAnne StubbeClass II ribonucleotide reductases: adenosylcobalamin as a radical chain initiator of a reaction with a chain length of one
Astrid Gräslund
Formation and reactions of the iron/tyrosyl radical site in ribonucleotide reductase
Marc Fontecave
The anaerobic ribonucleotide reductase: a radical/iron-sulfur enzyme
Joan B. Broderick, Timothy F. Henshaw, and Sheila S. Smith
Pyruvate formate-lyase activase: iron-sulfur clusters in radical generation
Metals in Medicine
Nicholas FarrellStructurally novel platinum-based drugs in the clinic. Toward a new paradigm
Trevor W. Hambley, Susan J. Berners-Price, Murray S. Davies, Connie I. Diakos, Hui Meng Er, Ronald R. Fenton, Edwina C. H. Ling, Vivienne P. Munk, and Evonne M. Rezler
What controls Pt/DNA interactions?
Randall B. Lauffer
Biophysical tuning and targeting of gadolinium(III) chelates for MRI
Thomas J. Meade
Seeing is believing: monitoring in vivo gene expression by magnetic resonance imaging
O2 Toxicity
Anne-Frances Miller, Aaron L. Schwartz, and Carrie K. VanceMechanisms of redox tuning in Fe- and Mn-superoxide dismutases
Michael J. Maroney, Suranjan B. Choudhury, Jin-Won Lee, Gerard Davidson, Yang-In Yim, Kurethara Bose, Manju L. Sharma, Sa-Ouk Kang, and Diane E. Cabelli
A SOD story: The structure and function of the NiSOD active site
Miguel Teixeira, Célia Romão, Cláudio Gomes, Jean LeGall, and A. V. Xavier
New metalloproteins involved in oxygen stress response in anaerobes
Joan Selverstone Valentine, Edith Butler Gralla, Joy J. Goto, Hongbin Liu, and Haining Zhu
Copper-zinc superoxide dismutase and ALS
[Sunday] [Monday] [Wednesday] [Thursday] [Friday]